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Our technology
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FEDS: Real-time, non-destructive visualization of DNA supercoiling
Bacterial DNA is more compacted, or supercoiled, when they are active, and our technology allows to sense this DNA supercoiling and translate it into a fluorescent signal. At a glance, we can well whether a given cell is active. Read the publication |
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Towards the development of molecules that take control of our bacteria
With the capacity to visualize DNA supercoiling, we can identify new druggable targets at high throughput and manipulate bacterial behaviors by altering their DNA structure. And we've already found targets with untapped potential. Read the publication |
